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Differential effects of mineralocorticoid blockade on the hypothalamo-pituitary-adrenal axis in pregnant and nonpregnant ewes

During pregnancy, plasma ACTH and cortisol are chronically increased; this appears to occur through a reset of hypothalamo-pituitary-adrenal (HPA) activity. We have hypothesized that differences in mineralocorticoid receptor activity in pregnancy may alter feedback inhibition of the HPA axis. We tes...

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Autors principals: Lingis, Melissa, Richards, Elaine M., Keller-Wood, Maureen
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064009/
https://ncbi.nlm.nih.gov/pubmed/21205934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00560.2010
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