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Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis
Systemic sclerosis (SSc) is an autoimmune connective tissue disorder characterized by oxidative stress, impaired vascular function, and attenuated angiogenesis. The tight-skin (Tsk(−/+)) mouse is a model of SSc that displays many of the cellular features of the clinical disease. We tested the hypoth...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063974/ https://ncbi.nlm.nih.gov/pubmed/21160034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00123.2010 |
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