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β(4)-Subunit increases Slo responsiveness to physiological Ca(2+) concentrations and together with β(1) reduces surface expression of Slo in hair cells

Changing kinetics of large-conductance potassium (BK) channels in hair cells of nonmammalian vertebrates, including the chick, plays a critical role in electrical tuning, a mechanism used by these cells to discriminate between different frequencies of sound. BK currents are less abundant in low-freq...

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Bibliografske podrobnosti
Main Authors: Bai, Jun-Ping, Surguchev, Alexei, Navaratnam, Dhasakumar
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063969/
https://ncbi.nlm.nih.gov/pubmed/21178105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00449.2010
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