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Leukocyte DNA Methylation Signature Differentiates Pancreatic Cancer Patients from Healthy Controls

Pancreatic adenocarcinoma (PaC) is one of most difficult tumors to treat. Much of this is attributed to the late diagnosis. To identify biomarkers for early detection, we examined DNA methylation differences in leukocyte DNA between PaC cases and controls in a two-phase study. In phase I, we measure...

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Main Authors: Pedersen, Katrina S., Bamlet, William R., Oberg, Ann L., de Andrade, Mariza, Matsumoto, Martha E., Tang, Hui, Thibodeau, Stephen N., Petersen, Gloria M., Wang, Liang
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063802/
https://ncbi.nlm.nih.gov/pubmed/21455317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018223
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