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Distinct Roles of Cdc42 in Thymopoiesis and Effector and Memory T Cell Differentiation

Cdc42 of the Rho GTPase family has been implicated in cell actin organization, proliferation, survival, and migration but its physiological role is likely cell-type specific. By a T cell-specific deletion of Cdc42 in mouse, we have recently shown that Cdc42 maintains naïve T cell homeostasis through...

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Détails bibliographiques
Auteurs principaux: Guo, Fukun, Zhang, Shuangmin, Tripathi, Pulak, Mattner, Jochen, Phelan, James, Sproles, Alyssa, Mo, Jun, Wills-Karp, Marsha, Grimes, H. Leighton, Hildeman, David, Zheng, Yi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063799/
https://ncbi.nlm.nih.gov/pubmed/21455314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018002
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