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Effects of Nickel Treatment on H3K4 Trimethylation and Gene Expression

Occupational exposure to nickel compounds has been associated with lung and nasal cancers. We have previously shown that exposure of the human lung adenocarcinoma A549 cells to NiCl(2) for 24 hr significantly increased global levels of trimethylated H3K4 (H3K4me3), a transcriptional activating mark...

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Hlavní autoři: Tchou-Wong, Kam-Meng, Kiok, Kathrin, Tang, Zuojian, Kluz, Thomas, Arita, Adriana, Smith, Phillip R., Brown, Stuart, Costa, Max
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063782/
https://ncbi.nlm.nih.gov/pubmed/21455298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017728
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