Effects of Nickel Treatment on H3K4 Trimethylation and Gene Expression

Occupational exposure to nickel compounds has been associated with lung and nasal cancers. We have previously shown that exposure of the human lung adenocarcinoma A549 cells to NiCl(2) for 24 hr significantly increased global levels of trimethylated H3K4 (H3K4me3), a transcriptional activating mark...

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Detalhes bibliográficos
Main Authors: Tchou-Wong, Kam-Meng, Kiok, Kathrin, Tang, Zuojian, Kluz, Thomas, Arita, Adriana, Smith, Phillip R., Brown, Stuart, Costa, Max
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063782/
https://ncbi.nlm.nih.gov/pubmed/21455298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017728
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