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On the Origin of DNA Genomes: Evolution of the Division of Labor between Template and Catalyst in Model Replicator Systems

The division of labor between template and catalyst is a fundamental property of all living systems: DNA stores genetic information whereas proteins function as catalysts. The RNA world hypothesis, however, posits that, at the earlier stages of evolution, RNA acted as both template and catalyst. Why...

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Détails bibliographiques
Auteurs principaux: Takeuchi, Nobuto, Hogeweg, Paulien, Koonin, Eugene V.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063752/
https://ncbi.nlm.nih.gov/pubmed/21455287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002024
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