4-Oxo-2-nonenal (4-ONE): Evidence of Transient Receptor Potential Ankyrin 1-Dependent and -Independent Nociceptive and Vasoactive Responses In Vivo

This study explores the in vivo effects of the proposed transient receptor potential ankyrin 1 (TRPA1) agonist 4-oxo-2-nonenal (4-ONE). Pharmacological inhibitors and genetically modified mice were used to investigate the ability of 4-ONE to act via TRPA1 receptors and possible mechanisms involving...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Graepel, Rabea, Fernandes, Elizabeth S., Aubdool, Aisah A., Andersson, David A., Bevan, Stuart, Brain, Susan D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2011
Gaiak:
Neuropharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063740/
https://ncbi.nlm.nih.gov/pubmed/21205926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.172403
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