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The High-Affinity cAMP-Specific Phosphodiesterase 8B Controls Steroidogenesis in the Mouse Adrenal Gland

The functions of the phosphodiesterase 8B (PDE8) family of phosphodiesterases have been largely unexplored because of the unavailability of selective pharmacological inhibitors. Here, we report a novel function of PDE8B as a major regulator of adrenal steroidogenesis using a genetically ablated PDE8...

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Detalles Bibliográficos
Main Authors: Tsai, Li-Chun Lisa, Shimizu-Albergine, Masami, Beavo, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063732/
https://ncbi.nlm.nih.gov/pubmed/21187369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.069104
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