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The Penultimate Arginine of the Carboxyl Terminus Determines Slow Desensitization in a P2X Receptor from the Cattle Tick Boophilus microplus

P2X ion channels have been functionally characterized from a range of eukaryotes. Although these receptors can be broadly classified into fast and slow desensitizing, the molecular mechanisms underlying current desensitization are not fully understood. Here, we describe the characterization of a P2X...

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Detalhes bibliográficos
Main Authors: Bavan, Selvan, Farmer, Louise, Singh, Shire K., Straub, Volko A., Guerrero, Felix D., Ennion, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063728/
https://ncbi.nlm.nih.gov/pubmed/21212138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.070037
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