The LIN-15A and LIN-56 Transcriptional Regulators Interact to Negatively Regulate EGF/Ras Signaling in Caenorhabditis elegans Vulval Cell-Fate Determination

The restricted expression of epidermal growth factor (EGF) family ligands is important for proper development and for preventing cancerous growth in mammals. In Caenorhabditis elegans, the class A and B synthetic multivulva (synMuv) genes redundantly repress expression of lin-3 EGF to negatively reg...

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Main Authors: Davison, Ewa M., Saffer, Adam M., Huang, Linda S., DeModena, John, Sternberg, Paul W., Horvitz, H. Robert
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2011
Assuntos:
Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063674/
https://ncbi.nlm.nih.gov/pubmed/21196525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.124487
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