Altered (13)C glucose metabolism in the cortico–striato–thalamo–cortical loop in the MK-801 rat model of schizophrenia

Using a modified MK-801 (dizocilpine) N-methyl--aspartic acid (NMDA) receptor hypofunction model for schizophrenia, we analyzed glycolysis, as well as glutamatergic, GABAergic, and monoaminergic neurotransmitter synthesis and degradation. Rats received an injection of MK-801 daily for 6 days and on...

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Hlavní autoři: Eyjolfsson, Elvar M, Nilsen, Linn Hege, Kondziella, Daniel, Brenner, Eiliv, Håberg, Asta, Sonnewald, Ursula
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063632/
https://ncbi.nlm.nih.gov/pubmed/21081956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.193
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