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Preclinical drug evaluation for combination therapy in acute stroke using systematic review, meta-analysis, and subsequent experimental testing

There is some evidence that in animal models of acute ischaemic stroke, combinations of neuroprotective agents might be more efficacious than the same agents administered alone. Hence, we developed pragmatic, empirical criteria based on therapeutic target, cost, availability, efficacy, administratio...

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書誌詳細
主要な著者: O'Collins, Victoria E, Macleod, Malcolm R, Cox, Susan F, Van Raay, Leena, Aleksoska, Elena, Donnan, Geoffrey A, Howells, David W
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063631/
https://ncbi.nlm.nih.gov/pubmed/20978519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.184
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