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Preclinical drug evaluation for combination therapy in acute stroke using systematic review, meta-analysis, and subsequent experimental testing

There is some evidence that in animal models of acute ischaemic stroke, combinations of neuroprotective agents might be more efficacious than the same agents administered alone. Hence, we developed pragmatic, empirical criteria based on therapeutic target, cost, availability, efficacy, administratio...

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Dades bibliogràfiques
Autors principals: O'Collins, Victoria E, Macleod, Malcolm R, Cox, Susan F, Van Raay, Leena, Aleksoska, Elena, Donnan, Geoffrey A, Howells, David W
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063631/
https://ncbi.nlm.nih.gov/pubmed/20978519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.184
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