Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity

In innate immune sensing, the detection of pathogen-associated molecular patterns by recognition receptors typically involve leucine-rich repeats (LRRs). We provide a categorization of 375 human LRR-containing proteins, almost half of which lack other identifiable functional domains. We clustered hu...

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Autors principals: Ng, Aylwin C. Y., Eisenberg, Jason M., Heath, Robert J. W., Huett, Alan, Robinson, Cory M., Nau, Gerard J., Xavier, Ramnik J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Colloquium Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063585/
https://ncbi.nlm.nih.gov/pubmed/20616063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000093107
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