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Low frequency of HER2 amplification and overexpression in early onset gastric cancer

BACKGROUND: The recent ToGA trial results indicated that trastuzumab is a new, effective, and well-tolerated treatment for HER2-positive gastric cancer (GC). Although GC mainly affects older patients, fewer than 10% of GC patients are considered early-onset (EOGC) (presenting at the age of 45 years...

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Autores principales: Moelans, Cathy B., Milne, Anya N., Morsink, Folkert H., Offerhaus, G. Johan A., van Diest, Paul J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063579/
https://ncbi.nlm.nih.gov/pubmed/21394646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-011-0021-0
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