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Heparin cofactor II-thrombin complex and dermatan sulphate:chondroitin sulphate ratio are biomarkers of short- and long-term treatment effects in mucopolysaccharide diseases

Early detection of mucopolysaccharidosis (MPS) is an important factor in treatment success; therefore, good disease biomarkers are vital. We evaluate heparin cofactor II-thrombin complex (HCII-T) as a biomarker in serum and dried blood spots (DBS) of MPS patients. Serum HCII-T and urine dermatan sul...

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Bibliographic Details
Main Authors: Langford-Smith, Kia Jane, Mercer, Jean, Petty, June, Tylee, Karen, Church, Heather, Roberts, Jane, Moss, Gill, Jones, Simon, Wynn, Rob, Wraith, J. Ed, Bigger, Brian W.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063559/
https://ncbi.nlm.nih.gov/pubmed/21170681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-010-9254-8
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