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COMPARISON OF THE EFFECTS OF AGING AND IL-6 ON THE HEPATIC INFLAMMATORY RESPONSE IN TWO MODELS OF SYSTEMIC INJURY: SCALD INJURY VERSUS I.P. LPS ADMINISTRATION

Regardless of age, a marked elevation in circulating IL-6 levels correlates with increased mortality after injury or an inflammatory challenge. We previously reported that aged IL-6 knockout mice given LPS have improved survival and reduced inflammatory response than LPS-treated aged wild type (WT)...

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Detalhes bibliográficos
Main Authors: Gomez, Christian R., Nomellini, Vanessa, Baila, Horea, Oshima, Kiyoko, Kovacs, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063471/
https://ncbi.nlm.nih.gov/pubmed/18636046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318180feb8
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