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The Rho pathway mediates transition to an alveolar type I cell phenotype during static stretch of alveolar type II cells
Stretch is an essential mechanism for lung growth and development. Animal models in which fetal lungs have been chronically over- or under-distended demonstrate a disrupted mix of type II and type I cells, with static overdistention typically promoting a type I cell phenotype. The Rho GTPase family,...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063400/ https://ncbi.nlm.nih.gov/pubmed/20220547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181dbc708 |
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