Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis

We report here the cleavage of the c-Jun N-terminal Kinase (JNK) pathway scaffold protein, JNK Interacting Protein-1 (JIP1), by caspases during both Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) and staurosporine-induced apoptosis in HeLa cells. During the initiation of apoptosis,...

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Hlavní autoři: Vaishnav, Mahesh, MacFarlane, Marion, Dickens, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Academic Press 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063339/
https://ncbi.nlm.nih.gov/pubmed/21237154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.01.011
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