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Alternative Splicing and Nonsense-Mediated RNA Decay Contribute to the Regulation of SHOX Expression
The human SHOX gene is composed of seven exons and encodes a paired-related homeodomain transcription factor. SHOX mutations or deletions have been associated with different short stature syndromes implying a role in growth and bone formation. During development, SHOX is expressed in a highly specif...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063249/ https://ncbi.nlm.nih.gov/pubmed/21448463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018115 |
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