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Development of Novel Zn(2+) Loaded Nanoparticles Designed for Cell-Type Targeted Drug Release in CNS Neurons: In Vitro Evidences

Intact synaptic function and plasticity are fundamental prerequisites to a healthy brain. Therefore, synaptic proteins are one of the major targets for drugs used as neuro-chemical therapeutics. Unfortunately, the majority of drugs is not able to cross the blood–brain barrier (BBB) and is therefore...

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Detalhes bibliográficos
Main Authors: Grabrucker, Andreas M., Garner, Craig C., Boeckers, Tobias M., Bondioli, Lucia, Ruozi, Barbara, Forni, Flavio, Vandelli, Maria Angela, Tosi, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063171/
https://ncbi.nlm.nih.gov/pubmed/21448455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017851
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