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Structural and Mechanistic Determinants of a Novel Site for Noncompetitive Inhibition of GluN2D-Containing NMDA Receptors

NMDA receptors are ionotropic glutamate receptors that mediate excitatory synaptic transmission and have been implicated in several neurological diseases. We have evaluated the mechanism of action of a class of novel subunit-selective NMDA receptor antagonists, typified by (E)-4-(6-methoxy-2-(3-nitr...

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Hlavní autoři: Hansen, Kasper B., Traynelis, Stephen F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063124/
https://ncbi.nlm.nih.gov/pubmed/21389220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5565-10.2011
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