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Tumor Necrosis Factor-α Signaling Maintains the Ability of Cortical Synapses to Express Synaptic Scaling

Glial tumor necrosis factor-α (TNFα) is essential for scaling up of synapses during prolonged activity blockade, but whether TNFα is an instructive or permissive signal is not known. Here we show in rat cortical neurons that the effects of TNFα and activity blockade are not additive; whereas TNFα in...

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Hlavní autoři: Steinmetz, Celine C., Turrigiano, Gina G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063078/
https://ncbi.nlm.nih.gov/pubmed/21048125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2210-10.2010
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