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Detecting the Surface Localization and Cytoplasmic Cleavage of Membrane-Bound Proteins
Polycystin-1 (PC1) is a large, membrane-bound protein that localizes to the cilia and is implicated in the common ciliopathy autosomal-dominant polycystic kidney disease. The physiological function of PC1 is dependent upon its subcellular localization as well as specific cleavages that release solub...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063071/ https://ncbi.nlm.nih.gov/pubmed/20362093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0091-679X(08)94011-5 |
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