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Room Temperature Stabilization of Oral, Live Attenuated Salmonella enterica serovar Typhi-Vectored Vaccines

Foam drying, a modified freeze drying process, was utilized to produce a heat-stable, live attenuated Salmonella Typhi ‘Ty21a’ bacterial vaccine. Ty21a vaccine was formulated with pharmaceutically approved stabilizers, including sugars, plasticizers, amino acids, and proteins. Growth media and harve...

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Bibliografiske detaljer
Main Authors: Ohtake, Satoshi, Martin, Russell, Saxena, Atul, Pham, Binh, Chiueh, Gary, Osorio, Manuel, Kopecko, Dennis, Xu, DeQi, Lechuga-Ballesteros, David, Truong-Le, Vu
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062996/
https://ncbi.nlm.nih.gov/pubmed/21300096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.01.093
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