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Selective opioid agonist and antagonist competition for [(3)H]-naloxone binding in amphibian spinal cord

Opioids elicit antinociception in mammals through three distinct types of receptors designated as μ, κ and δ. However, it is not clear what type of opioid receptor mediates antinociception in non-mammalian vertebrates. Radioligand binding techniques were employed to characterize the site(s) of opioi...

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Detalhes bibliográficos
Main Authors: Newman, Leslie C., Wallace, David R., Stevens, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062938/
https://ncbi.nlm.nih.gov/pubmed/11082500
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