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Monitoring Aromatic ps-ns Dynamics in Proteins via (13)C Relaxation: Expanding Perturbation Mapping of the Rigidifying Core Mutation, V54A, in eglin c
Long-range effects, such as allostery, have evolved in proteins as a means of regulating function via communication between distal sites. An NMR-based perturbation mapping approach was used to more completely probe the dynamic response of the core mutation V54A in the protein eglin c by monitoring c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062916/ https://ncbi.nlm.nih.gov/pubmed/18393447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702330t |
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