Replication of Association of a Novel Insulin Receptor Gene Polymorphism with Polycystic Ovary Syndrome

OBJECTIVE: To evaluate association with polycystic ovary syndrome (PCOS) of 295 variants in 39 genes central to metabolic insulin signaling and glycogen synthase kinase-3β (GSK-3β) regulation, followed by replication efforts. DESIGN: Case-control association study, with discovery and replication coh...

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Hauptverfasser: Goodarzi, Mark O., Louwers, Yvonne V., Taylor, Kent D., Jones, Michelle R., Cui, Jinrui, Kwon, Soonil, Chen, Yii-Der I., Guo, Xiuqing, Stolk, Lisette, Uitterlinden, André G., Laven, Joop S.E., Azziz, Ricardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062664/
https://ncbi.nlm.nih.gov/pubmed/21300347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2011.01.015
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