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Sensitive and Precise Quantification of Insulin-Like mRNA Expression in Caenorhabditis elegans

Insulin-like signaling regulates developmental arrest, stress resistance and lifespan in the nematode Caenorhabditis elegans. However, the genome encodes 40 insulin-like peptides, and the regulation and function of individual peptides is largely uncharacterized. We used the nCounter platform to meas...

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Detalhes bibliográficos
Main Authors: Baugh, L. Ryan, Kurhanewicz, Nicole, Sternberg, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062572/
https://ncbi.nlm.nih.gov/pubmed/21445366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018086
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