Mutations in Complement Regulatory Proteins Predispose to Preeclampsia: A Genetic Analysis of the PROMISSE Cohort

BACKGROUND: Pregnancy in women with systemic lupus erythematosus (SLE) or antiphospholipid antibodies (APL Ab)—autoimmune conditions characterized by complement-mediated injury—is associated with increased risk of preeclampsia and miscarriage. Our previous studies in mice indicate that complement ac...

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Detalhes bibliográficos
Main Authors: Salmon, Jane E., Heuser, Cara, Triebwasser, Michael, Liszewski, M. Kathryn, Kavanagh, David, Roumenina, Lubka, Branch, D. Ware, Goodship, Tim, Fremeaux-Bacchi, Veronique, Atkinson, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062534/
https://ncbi.nlm.nih.gov/pubmed/21445332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001013
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