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Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer

MicroRNAs (miRNAs) are small regulatory RNAs that are essential in all studied metazoans. Research has focused on the prediction and identification of novel miRNAs, while little has been done to validate, annotate, and characterize identified miRNAs. Using Illumina sequencing, ∼20 million small RNA...

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Detalhes bibliográficos
Main Authors: Warf, M. Bryan, Johnson, W. Evan, Bass, Brenda L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062169/
https://ncbi.nlm.nih.gov/pubmed/21307183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2432311
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