In Vivo and In Vitro Aging Is Detrimental to Mouse Spermatogonial Stem Cell Function

The development of techniques to maintain the spermatogonial stem cell (SSC) in vivo and in vitro for extended periods essentially allows for the indefinite continuation of an individual germline. Recent evidence indicates that the aging of male reproductive function is due to failure of the SSC nic...

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Detalhes bibliográficos
Main Authors: Schmidt, Jonathan A., Abramowitz, Lara K., Kubota, Hiroshi, Wu, Xin, Niu, Zhiyv, Avarbock, Mary R., Tobias, John W., Bartolomei, Marisa S., Brinster, Ralph L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062037/
https://ncbi.nlm.nih.gov/pubmed/21191109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.110.088229
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