Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer

Genomic sequences encoding the 3′ exonuclease (proofreading) domains of both replicative DNA polymerases, pol delta and pol epsilon, were explored simultaneously in human colorectal carcinomas including six established cell lines. Three unequivocal sequence alterations, including one previously repo...

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Detalhes bibliográficos
Main Authors: Yoshida, Rintaro, Miyashita, Kaname, Inoue, Mayuko, Shimamoto, Akiyoshi, Yan, Zhao, Egashira, Akinori, Oki, Eiji, Kakeji, Yoshishiro, Oda, Shinya, Maehara, Yoshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061989/
https://ncbi.nlm.nih.gov/pubmed/21157497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.216
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