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Tim-3 expression on peripheral T cell subsets correlates with disease progression in hepatitis B infection

BACKGROUND AND OBJECTIVE: T-cell immunoglobulin domain and mucin domain-containing molecule-3 (Tim-3) represents a novel mechanism of T-cell dysfunction in chronic viral diseases. However, the role of Tim-3 in the pathogenesis of chronic hepatitis B (CHB) is not well understood. We investigated Tim-...

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Detalhes bibliográficos
Main Authors: Wu, Wei, Shi, Yu, Li, Jie, Chen, Feng, Chen, Zhi, Zheng, Min
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061941/
https://ncbi.nlm.nih.gov/pubmed/21392402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-113
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