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Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations

BACKGROUND: The objective of this study is to identify the critical formulation parameters controlling distribution and function for the rectal administration of microbicides in humans. Four placebo formulations were designed with a wide range of hydrophilic characteristics (aqueous to lipid) and rh...

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Detalhes bibliográficos
Main Authors: Wang, Lin, Schnaare, Roger L, Dezzutti, Charlene, Anton, Peter A, Rohan, Lisa C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061893/
https://ncbi.nlm.nih.gov/pubmed/21385339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-8-12
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