Crystal Structure of a Coiled-Coil Domain from Human ROCK I

The small GTPase Rho and one of its targets, Rho-associated kinase (ROCK), participate in a variety of actin-based cellular processes including smooth muscle contraction, cell migration, and stress fiber formation. The ROCK protein consists of an N-terminal kinase domain, a central coiled-coil domai...

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Main Authors: Tu, Daqi, Li, Yiqun, Song, Hyun Kyu, Toms, Angela V., Gould, Christopher J., Ficarro, Scott B., Marto, Jarrod A., Goode, Bruce L., Eck, Michael J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061879/
https://ncbi.nlm.nih.gov/pubmed/21445309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018080
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