Mis17 Is a Regulatory Module of the Mis6-Mal2-Sim4 Centromere Complex That Is Required for the Recruitment of CenH3/CENP-A in Fission Yeast

BACKGROUND: The centromere is the chromosome domain on which the mitotic kinetochore forms for proper segregation. Deposition of the centromeric histone H3 (CenH3, CENP-A) is vital for the formation of centromere-specific chromatin. The Mis6-Mal2-Sim4 complex of the fission yeast S. pombe is require...

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Autores principales: Shiroiwa, Yoshiharu, Hayashi, Takeshi, Fujita, Yohta, Villar-Briones, Alejandro, Ikai, Nobuyasu, Takeda, Kojiro, Ebe, Masahiro, Yanagida, Mitsuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061866/
https://ncbi.nlm.nih.gov/pubmed/21445296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017761
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