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TGF-β1 diminishes collagen production during long-term cyclic stretching of engineered connective tissue: Implication of decreased ERK signaling

Cyclic stretching and growth factors like TGF-β have been used to enhance extracellular matrix (ECM) production by cells in engineered tissue to achieve requisite mechanical properties. In this study, the effects of TGF-β1 were evaluated during long-term cyclic stretching of fibrin-based tubular con...

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Detalhes bibliográficos
Main Authors: Syedain, Zeeshan H., Tranquillo, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061833/
https://ncbi.nlm.nih.gov/pubmed/21251657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2010.12.007
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