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Frzb-1 Is a Secreted Antagonist of Wnt Signaling Expressed in the Spemann Organizer

Frzb-1 is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. Frzb-1 is widely expressed in adult mammalian tissues. In the Xenopus gastrula, it is expressed and regulated as a typical Spemann organizer component. Injec...

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Detalhes bibliográficos
Main Authors: Leyns, Luc, Bouwmeester, Tewis, Kim, Sung-Hyun, Piccolo, Stefano, De Robertis, Eddy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061830/
https://ncbi.nlm.nih.gov/pubmed/9118218
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