Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans

Inflammation and infiltration of immune cells in white adipose tissue have been implicated in the development of obesity-associated insulin resistance. Likewise, dysregulation of the fuel-sensing enzyme AMP-activated protein kinase (AMPK) has been proposed as a pathogenetic factor for these abnormal...

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Autors principals: Gauthier, Marie-Soleil, O’Brien, Elena L, Bigornia, Sherman, Mott, Melanie, Cacicedo, Jose M, Xu, X. Julia, Gokce, Noyan, Apovian, Caroline, Ruderman, Neil
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061625/
https://ncbi.nlm.nih.gov/pubmed/21130749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.11.127
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