Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles

BACKGROUND: Polybutylcyanoacrylate (PBCA) nanoparticles coated with polysorbate-80 have been extensively proposed for delivering drugs into the animal brain and have shown great potential for therapeutic applications. In this study, we made an attempt to deliver the chemotherapeutic drug, temozolomi...

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Autors principals: Tian, Xin-Hua, Lin, Xiao-Ning, Wei, Feng, Feng, Wei, Huang, Zhi-Chun, Wang, Peng, Ren, Lei, Diao, Yi
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2011
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061435/
https://ncbi.nlm.nih.gov/pubmed/21445277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S16570
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