Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice

Myelin loss and axonal degeneration predominate in many neurological disorders; however, methods to visualize them simultaneously in live tissue are unavailable. We describe a new imaging strategy combining video rate reflectance and fluorescence confocal imaging with coherent anti-Stokes Raman scat...

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Detalhes bibliográficos
Main Authors: Imitola, Jaime, Côté, Daniel, Rasmussen, Stine, Xie, X. Sunney, Liu, Yingru, Chitnis, Tanuja, Sidman, Richard L., Lin, Charles. P., Khoury, Samia J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers (SPIE) 2011
Assuntos:
Special Section on Coherent Raman Imaging Techniques and Biomedical Applications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061329/
https://ncbi.nlm.nih.gov/pubmed/21361672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3533312
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