Defective Osteogenic Differentiation in the Development of Osteosarcoma

Osteosarcoma (OS) is associated with poor prognosis due to its high incidence of metastasis and chemoresistance. It often arises in areas of rapid bone growth in long bones during the adolescent growth spurt. Although certain genetic conditions and alterations increase the risk of developing OS, the...

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Bibliographic Details
Main Authors: Wagner, Eric R., Luther, Gaurav, Zhu, Gaohui, Luo, Qing, Shi, Qiong, Kim, Stephanie H., Gao, Jian-Li, Huang, Enyi, Gao, Yanhong, Yang, Ke, Wang, Linyuan, Teven, Chad, Luo, Xiaoji, Liu, Xing, Li, Mi, Hu, Ning, Su, Yuxi, Bi, Yang, He, Bai-Cheng, Tang, Ni, Luo, Jinyong, Chen, Liang, Zuo, Guowei, Rames, Richard, Haydon, Rex C., Luu, Hue H., He, Tong-Chuan
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2011
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Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061279/
https://ncbi.nlm.nih.gov/pubmed/21437219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/325238
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