Time Resolved 3D Molecular Tracking in Live Cells

We report a method for tracking individual quantum dot (QD) labeled proteins inside of live cells that uses four overlapping confocal volume elements and active feedback once every 5 milliseconds to follow three dimensional molecular motion. This method has substantial advantages over 3D molecular t...

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Hauptverfasser: Wells, Nathan P., Lessard, Guillaume A., Goodwin, Peter M., Phipps, Mary E., Cutler, Patrick J., Lidke, Diane S., Wilson, Bridget S., Werner, James H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061257/
https://ncbi.nlm.nih.gov/pubmed/20957984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl103247v
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