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Adenosine deaminase mRNA expression is regulated posttranscriptionally during differentiation of HL-60 cells.

The expression of the enzyme adenosine deaminase (ADA) decreases in the course of the differentiation of the human promyelocytic leukemic cell line HL-60, dependent on the pathway chosen. Differentiation to monocytes as induced by the phorbol ester TPA leads to a 50% reduction of enzyme activity. In...

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Bibliographische Detailangaben
Hauptverfasser: Berkvens, T M, Schoute, F, van Ormondt, H, Khan, P M, van der Eb, A J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC306124/
https://ncbi.nlm.nih.gov/pubmed/3306603
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