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Synthesis and Evaluation of 15-(4-(2-[(18)F]Fluoroethoxy)phenyl)pentadecanoic Acid: a Potential PET Tracer for Studying Myocardial Fatty Acid Metabolism

15-(4-(2-[(18)F]fluoroethoxy)phenyl)pentadecanoic acid ([(18)F]7) was synthesized as a PET probe for assessing myocardial fatty acid metabolism. The radiosynthesis of [(18)F]7 was accomplished using a two step reaction, starting with the corresponding tosylate ester, methyl 15-(4-(2-(tosyloxy)ethoxy...

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Detalhes bibliográficos
Main Authors: Tu, Zhude, Li, Shihong, Sharp, Terry L., Herrero, Pilar, Dence, Carmen S., Gropler, Robert J., Mach, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061239/
https://ncbi.nlm.nih.gov/pubmed/21070001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100343h
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