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Reverse engineering the (β/α)(8) barrel fold
The (β/α)(8) barrel is the most commonly occurring fold among protein catalysts. To lay a groundwork for engineering novel barrel proteins, we investigated the amino acid sequence restrictions at 182 structural positions of the prototypical (β/α)(8) barrel enzyme triosephosphate isomerase. Using com...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30612/ https://ncbi.nlm.nih.gov/pubmed/11248037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.041613598 |
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