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Synthesis and application of derivatizable oligonucleotides.

To investigate protein-DNA interactions, we have synthesized a versatile phthalimide-protected 5-(3-aminopropyl)-2'-deoxyuridine nucleoside probe. The modified residue was incorporated into deoxyoligonucleotides by automated synthesis. The standard oligonucleotide workup also exposed the penden...

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Bibliografiske detaljer
Main Authors: Gibson, K J, Benkovic, S J
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC306116/
https://ncbi.nlm.nih.gov/pubmed/2442728
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