Thermodynamic contributions of single internal rA·dA, rC·dC, rG·dG and rU·dT mismatches in RNA/DNA duplexes

The thermodynamic contributions of rA·dA, rC·dC, rG·dG and rU·dT single internal mismatches were measured for 54 RNA/DNA duplexes in a 1 M NaCl buffer using UV absorbance thermal denaturation. Thermodynamic parameters were obtained by fitting absorbance versus temperature profiles using the curve-fi...

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Bibliographic Details
Main Authors: Watkins, Norman E., Kennelly, William J., Tsay, Mike J., Tuin, Astrid, Swenson, Lara, Lee, Hyung-Ran, Morosyuk, Svetlana, Hicks, Donald A., SantaLucia, John
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061078/
https://ncbi.nlm.nih.gov/pubmed/21071398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq905
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