Učitavanje...
5′-end surveillance by Xrn2 acts as a shared mechanism for mammalian pre-rRNA maturation and decay
Ribosome biogenesis requires multiple nuclease activities to process pre-rRNA transcripts into mature rRNA species and eliminate defective products of transcription and processing. We find that in mammalian cells, the 5′ exonuclease Xrn2 plays a major role in both maturation of rRNA and degradation...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061060/ https://ncbi.nlm.nih.gov/pubmed/21036871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1050 |
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